Associate Scientist (Autoimmune Disease Biology)
91 Park Drive, Milton Park, Oxfordshire, OX14 4RY, UK
Join a pioneering biotech with a collegial atmosphere and a passion for harnessing every individual’s unique set of skills in our fight against disease.
At Immunocore, we have a vision to transform the way we understand and treat the most challenging medical conditions of our time, including cancer, autoimmune disorders and infection. In January 2022, in the U.S., we launched the world’s first T-cell receptor therapy, built on a novel technology designed to overcome the limitations of our natural immune systems.
Joining us at the most exciting time in our history, you will be part of a team that values trust and innovation, and that cherishes different ways of thinking.
We are looking for an enthusiastic and collaborative Associate Scientist to join our Autoimmune Disease Biology team. Based on our world leading TCR technology platform we are discovering and advancing novel targeted therapeutic agents for the treatment of Autoimmunity and Inflammation (ImmTAAIs).
This is a very exciting time to join the team as we’re pushing novel “first in class” approaches towards the clinic to help patients! It’s an opportunity for a passionate and creative team player who is keen to learn, innovate, collaborate and contribute to successes of a high-performance team within a pioneering, clinical-stage biotechnology company.
The candidate should have a BSc/MSc in Immunology, Inflammation Biology or related discipline. A strong interest in T cell biology and/or autoimmune immunology is a key requirement. Previous work experience in an autoimmune/inflammation research environment would be advantageous.
- Contribute to the Autoimmune biology platform by isolating and characterising various immune cells, maintaining cell lines and primary cells.
- Establish and conduct cellular screening assays to support optimisation of our ImmTAAI molecules.
- Characterise the impact of ImmTAAIs on Tregs functionality, support studies to demonstrate proof of concept and profile drug candidates.
- Analyse and report experimental results verbally and in writing. Actively participate in team meetings and lab organisation.
- Ability to run cell-based assays / functional assays to address key scientific questions.
- Proficiency in isolation of various immune cells (e.g. CD4+ T cells, Tregs), maintenance of cell lines.
- Experience in basic immunology techniques such as ELISA, T cell proliferation or flow cytometry analysis technologies.
- Strong team player with good communication skills, high attention to detail and good time management.
- Previous expertise in Treg biology and experimental techniques to characterize their impact on inflammation/autoimmunity.
Lead with Science and Discover What is Within:
- We Value Entrepreneurship and Diversity
- Respect, Trust, and Integrity
- Competitive compensation
- Private medical and dental benefits.
- 25 days Annual Leave and Bank Holidays
- 4x Salary Life Insurance
- 5% Pension Match
- Income Protection
- Parental Leave