Job description

Scientist (Infectious Disease)

Abingdon, Oxford

Scientist (Infectious Disease)

Immunocore, a pioneering, clinical-stage T cell receptor biotechnology company has an immediate opening for a Scientist to work on projects aimed at developing on cure strategies for HIV, HBV and other chronic viral infections. This is an excellent opportunity for a creative, motivated scientist to become part of a collaborative and dynamic team. The postholder should have a PhD in cell biology, virology, immunology, or related discipline (or equivalent level of experience) with demonstrable skills in problem-solving, attention to detail, ability to work collaboratively and drive to contribute to the team goals of innovating in preclinical disease biology models. Experience in flow cytometry would be an advantage.

This is a very exciting opportunity for a passionate and creative team player who is keen to learn, innovate, collaborate and contribute to successes of a high-performance team within a pioneering, clinical-stage biotechnology company.

 

KEY RESPONSIBILITIES 

  • Execute experiments to address key scientific questions enabling project progression, utilizing flow cytometry, ELISpots and ELISAs. Work will require handling human viruses. Some work will be conducted in a Containment Level 3 (CL3) facility.
  • Make detailed observations, analyse data and interpret results. Demonstrate scientific rigor in assessing data.
  • Maintain accurate records of all work, completing laboratory notebooks on time and following company procedures.
  • Continually strive to increase knowledge in relevant fields, in HIV/HBV functional cure in particular, through review of the scientific literature, discussion with IMC scientists both within and outside the infectious disease department and attending relevant seminars.
  • Effectively present results at internal meetings.
  • Understand priorities and scheduled objectives, alerting managers to any perceived risks or delays.
  • Work effectively in a matrixed team structure under general direction. Work will be reviewed against objectives for accuracy, completeness and sound judgement.
  • Compliance with the Company’s Health and Safety policies, especially within the CL3 laboratory environment, through following risk assessments, maintaining CL3 competency and training records, attending CL3 users’ meetings or reviewing meeting minutes; compliance with Human Tissue Authority requirements

 

EXPERIENCE AND KNOWLEDGE

  • Experience culturing primary cells and cell lines.
  • Flow cytometry expertise.
  • Experience with ELISAs, ELISpots and other 96-well format assays.
    • Expertise handling infectious agents is desirable but is not required as training will be provided. Applicant should feel comfortable with the idea of working with blood-borne viruses under CL3 conditions.
  • Experience with PCR
  • Knowledge / expertise in HIV/HBV virology and in vitro infection models is desirable but not a requirement as training will be provided
  • Worked in a bench-based laboratory environment with competence in key techniques relevant to the department
  • Competent in the safe use of general laboratory equipment
  • Recorded results in a concise and timely way, and in compliance with agreed standards
  • Learnt about new practices based through observation, self-learning and an enquiring mind
  • Worked and contributed effectively in a diverse team environment
  • Presented results and scientific practices
  • Excellent communication and organisational skills
  • Attention to detail
  • Scientific curiosity; interest in learning new things and taking on added responsibility.

 

Desirable 

  • Knowledge of Immunology
  • Able to meaningfully contribute on occasion to scientific team discussions, in particular with regards to the interpretation of their own data

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