Job description

Scientist - Display Technologies

91 Park Drive, Milton Park, Oxfordshire, OX14 4RY, UK

Immunocore is a late-stage biotechnology company pioneering the development of a novel class of TCR bispecific immunotherapies designed to treat a broad range of diseases, including cancer, infection and autoimmune disease. We are developing a deep pipeline in multiple therapeutic areas, including five clinical stage programs in oncology and infectious disease, advanced pre-clinical programs in autoimmune disease and multiple earlier pre-clinical programs.

It is an exciting time to join Immunocore. Our most advanced oncology therapeutic candidate, tebentafusp, has demonstrated an overall survival benefit in a randomized Phase 3 clinical trial in metastatic uveal melanoma, a cancer that has historically proven to be insensitive to other immunotherapies. The company also recently completed its Initial Public Offering and was listed on the NASDAQ.

 

Job role

The Protein Science Research Department is now seeking a Scientist to join the Display Technologies Team. As a part of the team, you will contribute to the development and improvement of the Immunocore’s T-cell Receptor discovery technology encompassing the fields of phage and mammalian display. This is an exciting opportunity for a motivated and open-minded individual to contribute and grow in an open and team-oriented environment in one of the UK’s leading biotechnology companies.

Key responsibilities:

  • Applying molecular biology and cell biology skills to develop and maintain Immunocore’s phage and mammalian display platforms
  • Analyses of TCR library outputs using appropriate set of scientific tools (sequencing, ELISA, flow cytometry etc.)
  • Collaborate cross-functionally and ensure efficient communication of the research data to the relevant people
  • Analyses and reporting of the experimental results verbally and in writing
  • Maintaining accurate records of all work by completing laboratory notebooks on time, following Company procedures
  • Ensuring that laboratory equipment is operated in accordance with safety and risk guidelines; acting promptly to report any faults or problems to the relevant member of staff
  • Maintaining and increasing technical knowledge in relevant fields through self-study, observation, attending relevant conferences and training courses

Experience and Knowledge:

To succeed in this role, you should have technical proficiency and background in the areas of molecular and cell biology and immunology

Desirable skills:

  • Experience with molecular cloning of DNA constructs, including primer design, PCR and DNA purification and analyses
  • Experience in DNA sequence analyses
  • Experience in screening protein display libraries and analysing output data.
  • Experience in flow cytometry.
  • Experience in cell biology with knowledge of T cell biology
  • Knowledge of Immunology

Education and qualifications:

  • Essential: BSc. Or MSc. in protein engineering, biochemistry, molecular biology or related discipline
    • Desirable: PhD in related discipline
    • Desirable: experience within a drug discovery industrial environment

 

 

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