Job description

Senior Scientist (Antibody Research)

91 Park Drive, Milton Park, Oxfordshire, OX14 4RY, UK

SENIOR SCIENTIST - ANTIBODY RESEARCH 

Join a pioneering biotech with a collegial atmosphere and a passion for harnessing every individual’s unique set of skills in our fight against disease.

At Immunocore, we have a vision to transform the way we understand and treat the most challenging medical conditions of our time, including cancer, autoimmune disorders and infection. In January 2022, in the U.S., we launched the world’s first T-cell receptor therapy, built on a novel technology designed to overcome the limitations of our natural immune systems.

Joining us at the most exciting time in our history, you will be part of a team that values trust and innovation, and that cherishes different ways of thinking.

The Role:

  • Do you love conducting experiments, observing, interpreting and responding to results?
  • Are you passionate about maintaining and increasing technical knowledge in relevant fields through self-study, observation, attending relevant conferences and training courses?
  • Is ensuring that laboratory equipment is operated in accordance with safety and risk guidelines; acting promptly to report any faults or problems to the relevant member of staff, your forte?
  • Do you place a real emphasis on operating in accordance with Health and Safety policies, especially within a laboratory environment?

Responsibilities:

  • Perform immunological assays such as ELISpot/ELISA, killing assays and FACS using multiple cell types.
  • On-board a range of cell assays appropriate to the functional effector being assessed and provide guidance and input to research and pre-clinical scientists.
  • Design and implementation of high-throughput screening assays for potency and specificity assessment.
  • Transfer of stablished screening assays to automated platforms.
  • Manage/maintain multiple cell lines.
  • Generate concise reports on-the-fly as data is generated and adapt assays to return most information-rich data.
  • Assimilate multiparameter data and disseminate data in an efficient way.
  • Able to meaningfully contribute to scientific team discussions, in particular with regards to the interpretation of data.
  • Knowledge of Immunology and experience of performing immunological assays

 Experience and Knowledge:

  • Experienced in cell-based assay development and assay miniaturisation.
  • Experienced in automation and use of liquid handling robots (e.g. Hamilton robotic platform or similar) to increase functional assay efficiency.
  • Experienced in assay transfer to automated platforms
  • Previous experience working with T cells/lymphocyte assays or immunological assays
  • Adept at co-ordinating assay management across functions.
  • Previous experience in screening biotherapeutics (e.g. antibodies, bi-/multi-specifics) beneficial.

Qualifications: 

  • Essential: BSc. Or MSc. in protein engineering, biochemistry, molecular biology or related discipline
  • Desirable: PhD in related discipline
  • Desirable: Relevant industrial or post-doctoral academic experience

Lead with Science and Discover What is Within:

  • We Value Entrepreneurship and Diversity
  • Respect, Trust, and Integrity
  • Competitive compensation
  • Private medical and dental benefits.
  • 25 days Annual Leave and Bank Holidays
  • 4x Salary Life Insurance
  • 5% Pension Match
  • Income Protection
  • Parental Leave

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