Job description

Senior Scientist – Pipeline Biology, Preclinical (12 mth contract)

91 Park Drive, Milton Park, Oxfordshire, OX14 4RY, UK

Immunocore is a late-stage biotechnology company pioneering the development of a novel class of TCR bispecific immunotherapies designed to treat a broad range of diseases, including cancer, infection, and autoimmune disease. We are developing a deep pipeline in multiple therapeutic areas, including five clinical stage programs in oncology and infectious disease, advanced pre-clinical programs in autoimmune disease and multiple earlier pre-clinical programs.

It is an exciting time to join Immunocore. Our most advanced oncology therapeutic candidate, tebentafusp, has demonstrated an overall survival benefit in a randomized Phase 3 clinical trial in metastatic uveal melanoma, a cancer that has historically proven to be insensitive to other immunotherapies. The company also recently completed its Initial Public Offering and was listed on the NASDAQ.

We are seeking highly motivated Senior Scientists to join our Pipeline Biology team. This is a 12 months contract to cover maternity leave. 

Key Responsibilities:

  • Conduct and analyse standard cell biology assays supporting ImmTAX screening and/or preclinical studies in accordance with set timelines.
  • Lead preclinical efforts for specific programmes/projects, representing the department within the multidisciplinary programme team and working in collaboration with representatives from other functions.
  • Proactively suggest lines of investigation in drug discovery projects and contribute to process enhancement activities by suggesting new technologies and/or developing new methodologies.
  • Present or contribute to communication of results, e.g. presentations in meetings, preclinical study report writing.
  • Establish and coordinate operational processes for Cell Biology laboratories and equipment as part of a small team of Senior Scientists.
  • Mentor or line manage junior staff, leading by example to foster company values and culture within the team

Experience & Knowledge:

Essential

  • Worked in a bench-based laboratory environment with recognized and established expertise in cell biology and immunology techniques (For example, cancer cell line and primary cell culture, T cell activation and redirected killing assays).
  • Ability to independently analyse and trouble-shoot the technical aspects of these core techniques.
  • Showing a strong analytical mind with the ability to interpret complex datasets and propose sound experimental strategies.
  • Recorded results in a concise and timely way, and in compliance with standards.
  • Good communication skills; presented detailed scientific findings or papers to different target audiences.
  • Ability to network between teams and disciplines.
  • Strong working relationships.

Desirable

  • Good understanding of preclinical drug discovery processes.
  • Experience in mentoring and supervision of junior staff.
  • Successfully led a small team project, formally or informally.
  • Proven publication record.
  • Kept abreast of current scientific literature and concepts.
  • Experience with preclinical studies for regulatory submissions.
  • Experience writing formal study reports, for example for regulatory documents.
  • Experience with molecular techniques, for example CRISPR

Education & Qualification

  • Essential: BSc. or MSc. in cell biology, immunology, molecular biology, protein engineering, biochemistry, or related discipline
  • Essential: Relevant industrial or post-doctoral academic experience
  • Desirable: PhD in related discipline

Lead with Science and Discover What is Within:

  • We Value Entrepreneurship, Diversity, Respect, Trust, and Integrity
  • Competitive compensation
  • Private medical and dental benefits.
  • 25 days Annual Leave and Bank Holidays
  • 4x Salary Life Insurance
  • 5% Pension Match
  • Income Protection
  • Parental Leave

Related Jobs

41 vacancies found