Job description

Scientist- Disease Biology- Infectious Disease

91 Park Drive, Milton Park, Oxfordshire, OX14 4RY, UK

SCIENTIST- DISEASE BIOLOGY

Join a pioneering biotech with a collegial atmosphere and a passion for harnessing every individual’s unique set of skills in our fight against disease.

At Immunocore, we have a vision to transform the way we understand and treat the most challenging medical conditions of our time, including cancer, autoimmune disorders and infection. In January 2022, in the U.S., we launched the world’s first T-cell receptor therapy, built on a novel technology designed to overcome the limitations of our natural immune systems.

Joining us at the most exciting time in our history, you will be part of a team that values trust and innovation, and that cherishes different ways of thinking.

As part of the Infectious Diseases team, you will have the opportunity to contribute towards cross functional efforts focussed on applying Immunocore’s ImmTAX® platform for the development of novel treatments for chronic infections, including HIV and HBV (Yang et al Mol Ther. 2016 Nov; 24(11): 1913–1925; Fergusson et al Hepatology . 2020 Nov;72(5):1528-1540). The team is involved in multiple stages of the drug discovery and development process, from target discovery all the way to clinical.

RESPONSIBILITIES:

Essential

  • Worked in a bench-based laboratory environment with competence in key techniques relevant to the department including:
    • culturing primary cells and cell lines.
    • Molecular techniques including some of the following: PCR, Mutagenesis, qPCR, Droplet Digital PCR.
    • Familiarity with technology/applications of Next generation sequencing.
  • Competent in the safe use of general laboratory equipment.
  • Recorded results in a concise and timely way, and in compliance with agreed standards.
  • Learnt about new practices based through observation, self-learning and an enquiring mind.
  • Worked and contributed effectively in a diverse team environment.
  • Presented results and scientific practices.
  • Able to meaningfully contribute on occasion to scientific team discussions, in particular with regards to the interpretation of their own data.
  • Excellent communication and organisational skills.
  • Attention to detail.
  • Scientific curiosity; interest in learning new things and taking on added responsibility.

 

KEY RESPONSIBILITIES – ROLE SPECIFIC

  • Execute experiments to address key scientific questions enabling project progression, utilizing range of techniques including flow cytometry, ELISpots, ELISAs, qPCR. Work will require handling human viruses. Some work will be conducted in a Containment Level 3 (CL3) facility.
  • Make detailed observations, analyse data and interpret results. Demonstrate scientific rigor in assessing data.
  • Maintain accurate records of all work, completing laboratory notebooks on time and following company procedures.
  • Continually strive to increase knowledge in relevant fields including HIV/HBV functional cure, through review of the scientific literature, discussion with IMC scientists and attending relevant seminars.
  • Effectively present results at internal meetings.
  • Understand priorities and scheduled objectives, alerting managers to any perceived risks or delays.
  • Work effectively in a matrixed team structure under general direction. Work will be reviewed against objectives for accuracy, completeness and sound judgement.
  • Compliance with the Company’s Health and Safety policies, especially within the CL3 laboratory environment, through following risk assessments, maintaining CL3 competency and training records, attending CL3 users’ meetings.
  • Compliance with Human Tissue Authority requirements.

EDUCATION & QUALIFICATIONS

  • PhD in molecular biology, cell biology, virology, immunology, or related discipline.
  • Alternatively, a B.S. or M.S. with significant work experience in relevant scientific areas and a record of scientific accomplishment (e.g. project progression, published manuscripts and/or abstracts).

Lead with Science and Discover What is Within:

  • We Value Entrepreneurship and Diversity
  • Respect, Trust, and Integrity
  • Competitive compensation
  • Private medical and dental benefits.
  • 25 days Annual Leave and Bank Holidays
  • 4x Salary Life Insurance
  • 5% Pension Match
  • Income Protection
  • Parental Leave

 

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