Job description

Formulation Scientist

91 Park Drive, Milton Park, Oxfordshire, OX14 4RY, UK

Formulation Scientist 

Join a pioneering biotech with a collegial atmosphere and a passion for harnessing every individual’s unique set of skills in our fight against disease.

At Immunocore, we have a vision to transform the way we understand and treat the most challenging medical conditions of our time, including cancer, autoimmune disorders and infection. In January 2022, in the U.S., we launched the world’s first T-cell receptor therapy, built on a novel technology designed to overcome the limitations of our natural immune systems.

Joining us at the most exciting time in our history, you will be part of a team that values trust and innovation, and that cherishes different ways of thinking.

The role:

To conduct and design experimental investigations to support a low dose parenteral bio-pharmaceutical in the development and management of integrated formulation strategies supporting Immunocore’s bio-pharmaceutical platforms. Formulations designed to meet different routes of delivery such as Sub-cutaneous.  The formulation role will cover early stressing studies, formulation excipient screening, CMC process support, drug substance and drug product through to compatibility with final patient delivery systems.  Support and direct IUS studies and progress the clinical programmes.  Support and respond to main stake holders for example Clinical and Regulatory teams in the delivery of the clinical strategies.

To work in close collaboration with the other Formulation scientists, CMC teams and related functions to input into the formulation related sections for regulatory filings, development reports and other development related documents.  Run new formulation methodologies supporting lyophilised presentations.

Key Responsibilities:

  • Conducting experiments, observing, interpreting and responding to results.
  • Maintaining and increasing technical knowledge in relevant fields through self-study, observation, attending relevant conferences and training courses.
  • Maintaining accurate records of all work by completing laboratory notebooks on time, following Company procedures
  • Ensuring that laboratory equipment is operated in accordance with safety and risk guidelines; acting promptly to report any faults or problems to the relevant member of staff.
  • Operating in accordance with the Company’s Health and Safety policies, especially within a laboratory environment.

Experience and Knowledge:

  • Background in recombinant protein or antibody formulation, analytical development or protein characterisation, with proven industry experience and exposure to formulation strategies.
  • Strong experience of developing sub-cutaneous formulations.
  • Experience in design of formulation studies, including the utilisation of design of experiments principles.
  • Strong expertise in electrophoretic or chromatographic assays and general biochemical lab techniques.
  • Experience in developing lyophilised formulation.

Qualifications:

  • Essential: MSc. In bio-manufacturing, protein engineering, biochemistry, molecular biology or related discipline.
  • Desirable: PhD in related discipline.

Benefits:

  • Competitive compensation
  • Private medical and dental benefits.
  • 25 days Annual Leave and Bank Holidays
  • 4x Salary Life Insurance
  • 5% Pension Match
  • Income Protection
  • Parental Leave

 

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