Pipeline

Built on our proprietary ImmTAX platform, we have a diverse pipeline of bispecific therapies across a broad range of indications.

Our pipeline includes clinical-stage programs in oncology and infectious diseases, as well as numerous pre-clinical projects

Stage of Clinical Development

Candidate

Target (HLA type)

Indication

IND-enabling

Phase 1

Phase 2

Phase 3

Approved

Catalyst

Tebentafusp

gp100 (A02)

gp100 (A02)

Adjuvant uveal (ocular)
melanoma

ATOM sponsored by EORTC

Phase 3

STATUS

Phase 3 Start l 2H24

2L+ Advanced cutaneous melanoma

TEBE-AM

Phase 2

STATUS

Phase 2 Data l 4Q24

Oncology

IMC-F106C

PRAME (A02)

PRAME (A02)

1L advanced cutaneous melanoma

PRISM-MEL-301

Phase 3

STATUS

Phase 3 Start l 2Q24

PRAME (A02)

2L+ cutaneous melanoma

Phase 1/2

STATUS

2Q24- 4Q2024


Phase 1
Clinical Data

PRAME (A02)

PRR ovarian<sup>1</sup>

Phase 1/2

STATUS

2Q24- 4Q2024


Phase 1
Clinical Data

PRAME (A02)

2L+ NSCLC

Phase 1/2

STATUS

2Q24- 4Q2024


Phase 1
Clinical Data

PRAME (A02)

Advanced endometrial

Phase 1/2

STATUS

Phase 1
Clinical Data


2Q24- 4Q2024

PRAME (A02)

Multiple solid tumors

Mono & combination arms

Phase 1/2

STATUS

2Q24- 4Q2024


Phase 1
Clinical Data

IMC-P115C

PRAME-HLE (A02)

PRAME-HLE (A02)

Multiple solid tumors

IND-enabling

STATUS

IND/CTA | Mid-24

IMC-T119C

PRAME (A24)

PRAME (A24)

Multiple solid tumors

IND-enabling

STATUS

IND/CTA | 4Q24

IMC-R117C

PIWIL1 (A02)

PIWIL1 (A02)

Colorectal and GI cancers

Phase 1

STATUS

Phase 1 Start | 2H 2024

Infectious Diseases

IMC-M113V<sup>2</sup>

Gag (A02)

Gag (A02)

Human Immunodeficiency Virus (HIV)

Phase 1

STATUS

MAD Data | 2H24

IMC-I109V

Envelope (A02)

Envelope (A02)

Hepatitis B Virus (HBV)

Phase 1

STATUS

Autoimmune Diseases

IMC-S118AI

PPIxPD1 (A02)

PPI (A02)

Type 1 Diabetes

IND-enabling

STATUS

Undisclosed

(universal)<sup>3</sup>

(universal)<sup>3</sup>

Dermatology

IND-enabling

STATUS

Date last updated: Apr. 26, 2024
New candidate added to pipeline January 2024.
1 Platinum refractory or resistant serous ovarian carcinoma. 2 Program is wholly owned, development costs being provided by the Bill & Melinda Gates Foundation (BMGF), Immunocore retains all development and commercialization rights in the developed world. 3 Program is not HLA restricted (i.e. universal for all populations)

KIMMTRAK

KIMMTRAK approved for HLA-A*02:01–positive metastatic or unresectable uveal melanoma

Disclaimer

All trademarks, company and product names or logos are the property of their respective owners. The efficacy and safety of the molecules under investigation have not yet been established. There is no guarantee that pipeline molecules will receive approval and become commercially available for the uses being investigated as drug development is uncertain and agents in development may be terminated along the development process. The above information is accurate as of November 2023.